1.
Org Lett
; 20(8): 2228-2231, 2018 04 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29600861
RESUMO
A novel transition-metal-free cleavage reaction of C-C triple bonds in aromatic alkynes with S8 and amides furnishes aryl thioamides in moderate to excellent yields. The remarkable features of this thioamidation include the metal-free cleavage of C-C triple bond, mild reaction conditions, as well as wide substrate scope that is particularly compatible with some internal aromatic alkynes and acetamides.
2.
Org Lett
; 17(9): 2046-9, 2015 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25860406
RESUMO
The palladium-catalyzed enantioselective intramolecular C-H arylation of N-(2-haloaryl)-P,P-diphenylphosphinic amides furnishes P-stereogenic phosphine oxide derivatives in 61-99% yield with 88-97% ee. The catalyst generated in situ from a TADDOL-derived phosphoramide ligand and Pd(dba)2 is optimum in terms of yield and enantioselectivities.